Shedding light on apoptosis at subcellular membranes
Andrews, D.W., Shedding Light on the Mechanisms of Action of Bcl-2 Family Proteins. Mitochondrial Dynamics and Physiology, Keystone Symposia on Molecular and Cellular Biology. Santa Fe, New Mexico, United States, February 19, 2014.
Read MoreBCL-2 family proteins: changing partners in the dance towards death
Kale J., Osterlund E.J., and Andrews, D.W. BCL-2 family proteins: changing partners in the dance towards death. (2018) Cell Death Differ. 25(1):65-80. doi: 10.1038/cdd.2017.186. Review.
Read MorePhosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance
Kale J., Kutuk O., Costa Brito G., Andrews T., Leber B., Letai A., and Andrews D.W. Phosphorylation switches Bax from promoting to inhibiting apoptosis increasing drug resistance. (2018) EMBO Rep. 19(9):e45235. doi: 10.15252/embr.201745235.
Read MoreMembrane Binding by tBid Initiates an Ordered Series of Events Culminating in Membrane Permeabilization by Bax
Membrane Binding by tBid Initiates an Ordered Series of Events Culminating in Membrane Permeabilization by Bax Volume 135, Issue 6, 12 December 2008, Pages 1074-1084 Jonathan F.Lovell1Lieven P.Billen1ScottBindner1AishaShamas-Din1CecileFradin12BrianLeber13David W.Andrews
Read MoreUnleashing Blocked Apoptosis in Cancer Cells: New MCL1 Inhibitors Find Their Groove
Leber, B., Kale, J., Andrews, D.W. Unleashing Blocked Apoptosis in Cancer Cells: New MCL1 Inhibitors Find Their Groove. (2018) Cancer Discovery. 8(12):1511-1514. doi: 10.1158/2159-8290.CD-18-1167.
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