Publications

MYC protein interactors in gene transcription and cancer

MYC protein interactors in gene transcription and cancer

Lourenco C, Resetca D, Redel C, Lin P, MacDonald AS, Ciaccio R, Kenney TMG, Wei Y, Andrews DW, Sunnerhagen M, Arrowsmith CH, Raught B, Penn LZ. MYC protein interactors in gene transcription and cancer. Nat Rev Cancer. 2021 Jun 29. doi: 10.1038/s41568-021-00367-9. Epub ahead of print.

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An amphipathic Bax core dimer forms part of the apoptotic pore wall in the mitochondrial membrane

An amphipathic Bax core dimer forms part of the apoptotic pore wall in the mitochondrial membrane

Lv F, Qi F, Zhang Z, Wen M, Piai A, Du L, Zhou L, Yang Y, Wu B, Liu Z, Rosario J, Pogmore JP, Chou JJ, Andrews DW, Jin J, Yang BO. An amphipathic Bax core dimer forms part of the apoptotic pore wall in the mitochondrial membrane. EMBO Journal. 2021 Jun 8:e106438. doi: 10.15252/embj.2020106438.    

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Pharmacological Targeting of Executioner Proteins: Controlling Life and Death

Pharmacological Targeting of Executioner Proteins: Controlling Life and Death

Pogmore JP, Uehling D, Andrews DW. Pharmacological Targeting of Executioner Proteins: Controlling Life and Death. J Med Chem. 2021 May 13;64(9):5276-5290. doi: 10.1021/acs.jmedchem.0c02200.

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Allosteric Regulation of BH3 Proteins in Bcl-xL Complexes Enables Switch-like Activation of Bax

Allosteric Regulation of BH3 Proteins in Bcl-xL Complexes Enables Switch-like Activation of Bax

Bogner C, Kale J, Pogmore J, Chi X, Shamas-Din A, Fradin C, Leber B, Andrews DW. Allosteric Regulation of BH3 Proteins in Bcl-xL Complexes Enables Switch-like Activation of Bax. Mol Cell. 2020 Feb 20;77(4):901-912.e9. doi: 10.1016/j.molcel.2019.12.025.

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Rapid 3D phenotypic analysis of neurons and organoids using data-driven cell segmentation-free machine learning

Mergenthaler P, Hariharan S, Pemberton JM, Lourenco C, Penn LZ, Andrews DW. Rapid 3D phenotypic analysis of neurons and organoids using data-driven cell segmentation-free machine learning. PLoS Comput Biol. 2021 Feb 22;17(2):e1008630. doi: 10.1371/journal.pcbi.1008630.

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Neuronal cell life, death, and axonal degeneration as regulated by the BCL-2 family proteins

Pemberton JM, Pogmore JP, Andrews DW. Neuronal cell life, death, and axonal degeneration as regulated by the BCL-2 family proteins. Cell Death Differ. 2021 Jan;28(1):108-122. doi: 10.1038/s41418-020-00654-2.

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