Publications

BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models

Vervloessem T, Sasi BK, Xerxa E, Karamanou S, Kale J, La Rovere RM, Chakraborty S, Sneyers F, Vogler M, Economou A, Laurenti L, Andrews DW, Efremov DG, Bultynck G. BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models. Cell Death Dis. 2020 Sep 17;11(9):769. doi: 10.1038/s41419-020-02944-6.

Read More

Highly Multiplexed Confocal Fluorescence Lifetime Microscope Designed for Screening Applications

Hirmiz N, Tsikouras A, Osterlund EJ, Richards M, Andrews DW, Fang Q. Highly Multiplexed Confocal Fluorescence Lifetime Microscope Designed for Screening Applications. IEEE Journal of Selected Topics in Quantum Electronics. 2020. doi: 10.1109/JSTQE.2020.2997834.

Read More

The mevalonate pathway is an actionable vulnerability of t(4;14)-positive multiple myeloma

Longo J, Smirnov P, Li Z, Branchard E, van Leeuwen JE, Licht JD, Haibe-Kains B, Andrews DW, Keats JJ, Pugh TJ, Trudel S, Penn LZ. The mevalonate pathway is an actionable vulnerability of t(4;14)-positive multiple myeloma. Leukemia. 2021 Mar;35(3):796-808. doi: 10.1038/s41375-020-0962-2.

Read More

A pilot window-of-opportunity study of preoperative fluvastatin in localized prostate cancer

Longo J, Hamilton RJ, Masoomian M, Khurram N, Branchard E, Mullen PJ, Elbaz M, Hersey K, Chadwick D, Ghai S, Andrews DW, Chen EX, van der Kwast TH, Fleshner NE, Penn LZ. A pilot window-of-opportunity study of preoperative fluvastatin in localized prostate cancer. Prostate Cancer Prostatic Dis. 2020 Dec;23(4):630-637. doi: 10.1038/s41391-020-0221-7.

Read More

The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells

Chi, X., Nguyen, D., Pemberton, J.M., Oesterlund, E.J., Liu, Q., Brahmbhatt, H., Zhang, Z., Lin, J., Leber, B. and Andrews, D.W. The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells. (2020). eLife, 9, e44525.

Read More

A reference library for assigning protein subcellular localizations by image-based machine learning

Schormann, W., Hariharan, S. and Andrews, D.W. A reference library for assigning protein subcellular localizations by image-based machine learning. (2020). The Journal of Cell Biology, 219(3).  

Read More