A small-molecule inhibitor of Bax and Bak oligomerization prevents genotoxic cell death and promotes neuroprotection

Niu X., Brahmbhatt H., Mergenthaler P., Zhang Z., Sang J., Daude M., Ehlert F.G.R., Diederich W.E., Wong E., Zhu W., Pogmore J.P, Nandy J.P., Satyanarayana M., Jimmidi R.K., Arya P., Leber B., Lin J., Culmsee C., Yi J., and Andrews, D.W., A small molecule inhibitor of both proapoptotic Bax and Bak oligomerization prevents genotoxic cell death and promotes neuroprotection.(2017) Cell Chemical Biology.24(4):493-506.e5. doi: 10.1016/j.chenbiol.2017.03.011.