Longo J, Hamilton RJ, Masoomian M, Khurram N, Branchard E, Mullen PJ, Elbaz M, Hersey K, Chadwick D, Ghai S, Andrews DW, Chen EX, van der Kwast TH, Fleshner NE, Penn LZ. A pilot window-of-opportunity study of preoperative fluvastatin in localized prostate cancer. Prostate Cancer Prostatic Dis. 2020 Dec;23(4):630-637. doi: 10.1038/s41391-020-0221-7.
![](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41391-020-0221-7/MediaObjects/41391_2020_221_Fig2_HTML.png?as=webp)
Serum and tissue measurements before and after fluvastatin treatment, and effects of fluvastatin on PCa cell death.
![](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41391-020-0221-7/MediaObjects/41391_2020_221_Fig3_HTML.png?as=webp)
Effects of fluvastatin on intratumoral proliferation and apoptosis.