Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells.
Saraon P, Snider J, Schormann W, Rai A, Radulovich N, Sánchez-Osuna M, Coulombe-Huntington J, Huard C, Mohammed M, Lima-Fernandes E, Thériault B, Halabelian L, Chan M, Joshi D, Drecun L, Yao Z, Pathmanathan S, Wong V, Lyakisheva A, Aboualizadeh F, Niu L, Li F, Kiyota T, Subramanian R, Joseph B, Aman A, Prakesch M, Isaac M, Mamai A, Poda G, Vedadi M, Marcellus R, Uehling D, Leighl N, Sacher A, Samaržija M, Jakopović M, Arrowsmith C, Tyers M, Tsao MS, Andrews D, Al-Awar R, Stagljar I. Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK...
Read MoreBcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis.
Rosa N, Ivanova H, Wagner LE 2nd, Kale J, Lemmens I, Karamanou S, Louros N, Shabardina V, Welkenhuyzen K, La Rovere R, Vandermarliere E, Hamada K, Ando H, Rousseau F, Schymkowitz J, Mikoshiba K, Economou A, Tavernier J, Andrews DW, Parys J, Yule DI, Bultynck G. Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis. Cell Death Differ. 2021 Oct 7. Accepted.
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