Featured Publication

Selected Review Publications:

Brahmbhatt H, Oppermann S, Osterlund EJ, Leber B, Andrews DW

Molecular Pathways: Leveraging the BCL-2 Interactome to Kill Cancer Cells--Mitochondrial Outer Membrane Permeabilization and Beyond

Clinical Cancer Research Vol 21June 2015

Abstract  Full Text  Adobe PDF

Xiaoke Chi, Justin Kale, Brian Leber and David W. Andrews

Regulating cell death at, on, and in membranes

Biochimica et Biophysica Acta Sep 2014, Vol 1843, Issue 9, 2100-2113

Abstract  Adobe PDF

C. Borner, David W. Andrews

The apoptotic pore on mitochondria: are we breaking through or still stuck?

Cell Death and Differentiation Feb 2014 Vol 21 187-191

Full Text  Adobe PDF

Aisha Shamas-DIn, Justin Kale, Brian Leber and David W. Andrews

Mechanisms of Action of Bcl-2 Family Proteins

Cold Spring Harbor Perspectives in Biology April 2013, Volume 5 Issue 4

Abstract  Full Text  Adobe PDF

Justin Kale, Qian Liu, Brian Leber, David W. Andrews

Shedding Light on Apoptosis at Subcellular Membranes

Cell December 2012, Volume 151 Issue 6 pp:1179-1184

Abstract  Full Text  Adobe PDF

Brian Leber, David W. Andrews

Closing in on the link between apoptosis and autophagy

F1000 Biol Reports December 2010, 2:88 (doi: 10.3410/B2-88)

Abstract  Full Text  Adobe PDF

Christian Bogner, Leber, B. and David W. Andrews

Apoptosis: embedded in membranes

Current Opinion in Cell Biology Volume 22, Issue 6, 2010, Pages 845851

Abstract  Full Text  Adobe PDF

Brian Leber,Fei Geng, Justin Kale and D W Andrews

Drugs targeting Bcl-2 family members as an emerging strategy in cancer

Expert Reviews in Molecular Medicine Vol 12 Dec 2010

Abstract  Full Text  Adobe PDF

L P Billen, A Shamas-Din, D W Andrews

Bid: a Bax-like BH3 protein

Oncogene 27, S93-S104 (30 July 2009)

Abstract Full Text Adobe PDF

Galluzzi L. et al. (Andrews, D.W. of 80 authors).

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes.

Cell Death and Differentiation. 16, 10931107

Abstract Full Text Adobe PDF

Dejuan Kong, Liping Xu, Yingjie Yu, Weijia Zhu, David W. Andrews, Yisang Yoon and Tuan H. Kuo

Regulation of Ca2+-induced permeability transition by Bcl-2 is antagonized by Drp1 and hFis

Molecular and Cellular Biochemistry 272: 187-199, 2005

Abstract Adobe PDF

Annis, M.G., Yethon, J.A., Leber, B. and Andrews, D.W. (2003)

There is more to life and death than mitochondria: Bcl-2 Proteins at the Endoplasmic Reticulum. 

Biochim Biophys Acta. 2004 Mar 1;1644(2-3):115-23.

Abstract Full Text Adobe PDF

Andrews, D.W

Protein origami for beginners. 

Dev Cell. 2002 Nov;3(5):608-10. Review.  

Abstract Full Text Adobe PDF

Legate KR, Andrews DW.

Assembly strategies and GTPase regulation of the eukaryotic and Escherichia coil translocons.

Biochem Cell Biol. 2001;79(5):593-601.

Abstract Adobe PDF

Andrews DW.

Transport across membranes: a question of navigation.

Cell. 2000 Jul 21;102(2):139-44.

Full Text Adobe PDF

Thomsen L, Robinson TL, Lee JC, Farraway LA, Hughes MJ, Andrews DW, Huizinga JD.

Interstitial cells of Cajal generate a rhythmic pacemaker current.

Nat Med. 1998 Jul;4(7):848-51. 

Abstract Adobe PDF

Millman JS, Andrews DW.

Switching the model: a concerted mechanism for GTPases in protein targeting.

Cell. 1997 May 30;89(5):673-6. Review. 

Abstract Full Text